Description
Opana ER 40 mg is the strongest available extended-release formulation of Oxymorphone Hydrochloride. It belongs to the family of medicines known as long-acting opioid analgesics and widely prescribed to manage severe pain. The E 40 yellow round pill is categorized as a controlled substance of Schedule II due to the tendency to abuse or misuse. The Opana ER 40 mg pill falls under the group of drugs which is known as opioid agonist painkillers, which are suitable for patients with conditions requiring constant pain control, such as:
- Cancer-related pain
- Severe musculoskeletal disorders
- Chronic back pain
- Neuropathic pain not managed by other medicines
Distinguishable short-acting painkillers, the generic Opana ER is formulated as an extended-release tablet and each dose lasts up to 12 hours, lessening the need for frequent dosing. The Round yellow E 40 pill works the same as various other narcotic medications, as well as acetaminophen, naproxen, cyclobenzaprine, Oxycodone, Tylenol, and Tramadol.
The 40 yellow pill is mostly advantageous for adults above 18 years old and suggested to start with a lower dose of 10mg to 20mg every 4-6 hours.
Key Points to Recall In Advance of the Opana ER 40mg
Function of the Opana ER 40mg Medicines
The generic Opana 40 tablet contains the active ingredient Oxymorphone, an extended-release form of an opioid pain reliever. It mainly reveals its analgesic abilities by attaching to mu-opioid receptors within the CNS. Through the initialization of these receptors, Oxymorphone modulates pain response and perception, eliciting a response that ends up relieving pain. In other words, we have to say that the 40 mg Opana ER capsule may convert the emotional reaction to pain and accordingly, the feeling of being painless remains.
How to Utilize the Round Yellow E 40 pill?
- Carefully read the available medication guide before starting the Opana ER and each time you get a refill.
- If you have any queries, ask your medical professional. Regularly use this medication exactly as directed.
- Use the E 40 yellow round tablet orally without food or an hour or two after eating as your doctor’s prescription.
- Swallow the extended-release capsules whole with enough water.
- Don’t lick, pre-soak, or wet the pills before putting them in your mouth.
- It is not safe to consume the E40 yellow pill with alcohol or other medicines.
- Safely store the medicine at room temperature between 68°F and 77°F (20°C and 25°C) away from light, heat, or moisture. Never keep it in the bathroom or kitchen.
Dosage of Opana Drug
This pain relief medicine is available in several dosages and comes in the form of an extended-release oral tablet and is designed to treat around-the-clock chronic pain that cannot be controlled with other therapies. It is available in both immediate-release and extended-release tablets.
Immediate-Release (IR) Tablet
- Opana IR 5mg
- Opana IR 10mg
Extended-Release (ER) Tablet
Are There Any Complications of generic Opana ER 40mg?
There are a few complications or risk factors associated with the E40 yellow tablet. Report to your medical professional after feeling some usual side effects, including headache, vomiting, drowsiness, dizziness, dryness in mouth, constipation, and itching. Seek emergency medical attention after experiencing the following critical side effects, including:
- Seizures
- Sleep apnea
- Allergic reactions
- Mental illness
- Low vision
- Difficulty in urinating
- Extreme stomach pain
- Fainting
- Changes in heartbeat
- Weight loss
- Loss of appetite
What Drugs Can Interact With E 40 yellow round pill?
The Opana ER 40mg capsule can interact with other drugs and can cause dangerous side effects, leading to death. Ensure that your pharmacist knows if you take any of the following drugs.
- Other narcotic pain relievers, including Hydrocodone, Oxycodone, Vicodin, and Percocet.
- Certain antibiotics
- Seizure medicines, like Gabapentin
- Several allergy drugs
- Various muscle relaxers, such as Cyclobenzaprine, Carisprodol (Soma)
- Multiple Sleeping pills
- HIV drugs
- Some CYP3A4 Inhibitors, as well as Ketoconazole, Clarithromycin
- Sedatives (anti-anxiety medicines)
- SSRIs, like Fluoxetine, Sertraline, and SNRIs, like Venlafaxine, Duloxetine
- Multiple stimulants (ADHD medication)
Overdose
An Opana ER overdose can be deadly, especially in a child or someone employing it without a prescription. In that situation, take immediate medical help or call your primary care provider to guide and provide a proper solution. Overdose symptoms may include:
- Pinpoint pupils
- Shallow breathing
- Serious drowsiness
- No breathing
What to Know Before Taking Opana ER 40?
Consumption of alcohol is prohibited during the 40 mg Opana pill as it will make you feel dizzy and may cause hazardous side effects. Before starting the treatment, check with your pharmacist if you are allergic to it. Report to your doctor if you are:
- Breathlessness or serious asthma
- Blockage in the intestines or stomach
Before starting your dose, don’t forget to tell the physician if you have ever had:
- Extreme seizures
- Breathing issues
- Sleep apnea
- A head injury
- Alcohol addiction
- Facing difficulty in urinating
- Mental illness
- Kidney/ liver disease
Your newborn child could be dependent upon the medicines if you use this pain relief drugs during pregnancy. It may cause life-threatening withdrawal symptoms. It is best if you don’t breastfeed while using Opana ER tablet.
In case you forget a dose, take it when you recall. Skip the missed dose if the time is close to the next scheduled dose. Never take a double dose to adjust the omitted dose. Unfortunately, if you have overdosed, seek emergency medical help to recover soon.
Exploring Other Substitutions
Some notable replacements are mentioned in the following.
Opioid Alternatives
Non-Opioid Alternatives
- Ibuprofen
- Naproxen
- Celecoxib
- Acetaminophen (Tylenol)
Non-Pharmacological Interventions
- Physical therapy
- Occupational therapy
- Heat and cold therapy
- Massage therapy
- Mind-body therapy
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